Saturday, February 24, 2024

Alvin J Siteman Cancer Center

Research At Siteman Cancer Center

Ryan Fields, MD, talks COVID-19 concerns for cancer patients

Siteman offers the expertise of more than 450 Washington University scientists and physicians whose research results are quickly incorporated into treatment options, including hundreds of therapeutic clinical trials.

Of particular note is Sitemans innovative research aimed at improving the survival of leukemia patients and reducing the treatment-related side effects they commonly experience. In addition, Siteman researchers are developing new approaches to detect and treat pancreatic cancer.

Other recognized research strengths include: genomics cancer imaging, prevention, and disparities and the use of the body’s immune system to fight cancer.

Siteman Cancer Center Stresses Multidisciplinary Approach To Care

For quality mesothelioma or lung cancer care in St. Louis, Missouri, theres no better destination than the citys world-famous Alvin J. Siteman Cancer Center. Siteman is the only Comprehensive Cancer Center in all of Missouri, meaning the National Cancer Institute has designated it as maintaining the highest standards of excellence in patient care, clinical research, cancer prevention, education and basic science.

Not only is Siteman consistently ranked by U.S. News & World Report as one of the nations best cancer treatment centers, its parent institutions, Barnes-Jewish Hospital and Washington University School of Medicine, both rank highly as well. The staff of Siteman and its affiliated locations includes more than 350 research scientists and physicians from these institutions. Every year, the hospital treats about 8,000 newly diagnosed cancer patients, receiving more than $165 million in cancer research and related training grants in the process.

This dedicated community of specialists, including doctors and surgeons, nurses and researchers, utilizes a multidisciplinary approach to patient care. This is certainly beneficial for diagnosing and treating mesothelioma and lung cancer patients. Siteman has a malignant mesothelioma treatment team and is one of very few facilities to have its own dedicated chest surgery unit.

Siteman Cancer Center Turns Latest Research Into Novel Treatments

Siteman is considered a leader in research for all cancer subtypes. But research for lung cancer and related conditions is a particular strength, as the program is actually ranked among the nations best.

The close partnership between Siteman and the medical and academic communities ensures the latest in diagnostic tests and cutting-edge treatments. The lung cancer specialists regularly participate in clinical cancer trials, such as Phase I/II, Open-Label, Randomized Study of the Safety, Efficacy and Pharmacokinetics of Erlotinib With or Without PF-02341066 in Patients with Advanced Non-Small Cell Adenocarcinoma of the Lung .

Patients are able to participate in more than 250 clinical studies involving such paths as nanotechnology, bioinformatics, chemoprevention, pharmacogenetics, gene therapy, proteomics, imaging, genomics and leukemia and lymphoma.

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Cancer Prevention And Control

Siteman and Washington University School of Medicine are actively engaged in many projects to prevent cancer in the St. Louis region and across the United States. These efforts include:

  • The Your Disease Risk website, an interactive tool that helps people estimate their risk of cancer, diabetes, heart disease, osteoporosis and stroke, and suggests preventative measures that help lower the likelihood of developing each disease.
  • Zuum, a free mobile app for iPad that estimates a person’s risk of cancer, heart disease, diabetes and other diseases, and offers customized tips for prevention and boosting one’s overall health.
  • “Together – Every Woman’s Guide to Preventing Breast Cancer,” a free e-book for iPads that provides practical, science-based advice for lowering breast cancer risk at nearly every stage of life.
  • Research examining cancer disparities, cancer communications and tobacco use.

Select Scientific Initiatives At Siteman Cancer Center


As leaders in sequencing the genomes of cancer patients and their tumor cells, Washington University scientists at Siteman have a unique perspective on the genetic changes that drive the development of cancer. These researchers and clinicians are engaged in studies to determine which drugs will work best for patients based on the genetic makeup of their tumors, including breast, lung, endometrial, and other forms of the disease.

  • Siteman has clinical programs that specialize in bone marrow and stem cell transplantation, gynecologic oncology, sarcoma, and neuro-oncology.
  • Public health and prevention scholars at the center are integrating evidence-based cancer control initiatives into clinical and public health practice, and exploring ways to improve tobacco control.
  • Engineers in optical imaging at Siteman are developing goggles that use near-infrared light to assist surgeons in visualizing tumors. The investigational technology relies on a biomarker that binds to cancer cells, causing the tumor to light up and become visible to surgeons wearing the goggles.

This profile was provided by Siteman Cancer Center.

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Who Can Get Screened For Lung Cancer

If youre 50-80 years old and have a smoking history of 20 pack years or more, you can get screened.

Examples of at least a 20 pack year smoking history: 1 pack per day for 20 years, three-quarters of a pack a day for 30 years or half a pack a day for 40 years. Calculate your pack year history

If you have smoked this amount or more, you may be eligible for lung cancer screening. Even if you quit smoking, you can get screened as long as you quit in the past 15 years

Treating Mesothelioma At Siteman Cancer Center

When treating mesothelioma, Sitemans physicians typically rely on surgery and radiation to treat local tumors. Meanwhile, chemotherapy is used for the whole body, as it can be directed toward cancerous cells that may break away from the source.

Mesothelioma treatments may also depend on the diseases stage. For instance, Stage I patients may undergo surgery to remove affected chest lining and tissues, followed by radiation therapy. However, patients with more advanced stages may undergo surgery to drain fluid in the chest, followed by radiation, chemotherapy or even combinations of these treatments. Palliative treatments, which are designed to improve quality of life by relieving the pain associated with symptoms, are used in conjunction with other treatments throughout the process of managing the disease.

Siteman surgeons are also utilizing biologic therapy , an experimental treatment in which certain substances are used to boost the patients own immune system to fight the cancer.

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Meet Our Cancer Experts

Surrounding yourself with a team of cancer doctors allows you to get the answers you need to make informed decisions about your care, with the sense of urgency you deserve. If youve been diagnosed with cancer, or youre already undergoing treatment, and youre unsure of what to do, the cancer doctors at CTCA will work with you to design a treatment plan thats personalized for your diagnosis and your individual needs, treating not just the disease but also helping you manage side effects and get back to life.

Together Group Gynecologic Cancer Support Group

Breast Cancer Survivor, Erica Griffin

TOGETHER is a wellness group for women with gynecological cancer that provides an opportunity for you to share feelings and experiences with other women who have gynecological cancer. Group members explore the healing process together. Meetings are free and open to gynecological cancer patients and their significant others and family members.If you are interested in TOGETHER meetings or would like more information, call 362-4180.

When: TBDWhere: Center for Advanced Medicine, 4921 Parkview Place, St. Louis, MO 63110, 3rd floor Farrell Conference Room #2

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Plaza Gift Shop/flower Shop

The Plaza Gift Shop/Flower Shop is located in the lobby of Barnes-Jewish Hospital South. All proceeds benefit Barnes-Jewish Hospital. The gift shop offers items frequently requested by patients as well as mens, womens and childrens clothing, accessories, gifts, boxed and bulk candy, fragrances, toys, greeting cards, stationery, jewelry, books, magazines and postage stamps. The flower shop carries fresh floral arrangements, potted plants and balloons.

  • Hours: 8 a.m. to 7:30 p.m. Monday to Friday, 10 a.m. to 5 p.m. Saturday and noon to 5 p.m. Sunday
  • To Place an Order:Shop online or call 314-362-4300 or toll-free 800-409-4485 for assistance. Delivery is available within Barnes-Jewish Hospital and the Center for Advanced Medicine. In addition, the Flower Shop delivers floral arrangements, plants and balloons throughout the metropolitan area and can wire orders worldwide.

What Are The Costs Of A Lung Cancer Screen

Costs may differ based on your specific benefit and coverage information, as well as the specific services you receive. Please contact your insurance provider to ask about your expected out-of-pocket costs.

Medicare currently covers the costs of lung cancer screening for eligible patients. Many private insurance companies do as well. In some cases, you may have to pay a portion of the costs.

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Our Lung Cancer Specialists

Our lung cancer screening program is the largest in Missouri, comprised of 12 fellowship-trained thoracic radiologists. Seven of these experts were members of the original National Lung Screening Trial , a lung cancer screening study. The study compared low-dose helical CT and standard chest X-ray as lung cancer screening methods. The study was published in 2003 in the New England Journal of Medicine. The NLST was a defining moment in lung cancer research, shedding light on the benefit of low-dose CT scanning. LDCT was linked to a 20 percent decrease in lung cancer deaths in both current and former smokers.

The Mallinckrodt Institute of Radiology at Washington University School of Medicine in St. Louis has one of the largest thoracic imaging and cardiac radiology services in the country. Our experts interpret about 120,000 chest radiographs, 12,000 chest CTs and performing 250 lung biopsies every year. They have unique expertise in thoracic MRI and are sought globally to speak on MRI of the chest.

Our thoracic radiologists are renowned for their accomplishments in lung cancer research and chest imaging. Our members include past presidents of the North American Society for Cardiovascular Imaging , the Society of Thoracic Radiology and the Society of Advanced Body Imaging . We have also had 2 members of the Fleischner Society, an esteemed international society dedicated to thoracic disease.

Education And Community Outreach

Alvin J. Siteman Cancer Center Myeloma Trials

In addition to treatment and research programs, Siteman is involved with community outreach, education and screening. Efforts include:

  • The Program for the Elimination of Cancer Disparities , which develops cancer prevention and awareness messages, reports research findings to the community, hosts continuing medical education events and engages in other activities.
  • Placing information about breast cancer and mammograms in Laundromats, where a study has shown it’s more likely to be seen than in other community settings by women who lack access to adequate health care.
  • A mobile mammography van that offers screenings by appointment in St. Louis and surrounding communities.

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Algonquin Highlands Heritage Map

Geographic location: Lot 4, Conc. A, Sherborne

Current address: 20130 Hwy 35 on St. Nora Lake

Date range:1944 – present

Interesting facts:

In 1944 the Province of Ontario and the University of Toronto Faculty of Forestry entered into a partnership to educate government personnel and university students. For many years the site was known as the Ranger School and later, the Ontario Forest Technical Training School. Many courses were taught to government personnel. Students from various faculties at the University came to the school each year on field trips.

In 1969, the schools curriculum of resource management was taken over by Ontarios colleges and universities. That was the first time the future of the property that would become the Frost Centre, was in doubt. In 1974, Ontario Premiere William G. Davis announced that the facility would be developed as a demonstration area in resources management, education and recreation and would be called The Leslie M. Frost Natural Resources Centre. The Centre became the first outdoor education Centre in the province dedicated to environmental and resource management education. It was also the first Centre to have a large crown land management unit , associated with it for research in and demonstration of resource management, recreation and public education.

Are You Ready To Quit Smoking

Quitting smoking lowers your risk of getting lung cancer and other diseases of the lungs, heart, blood, and brain.

You can get FREE help quitting, at:

  • Tobacco Quitline: Individual telephone counseling, 1-800-QUIT-NOW .
  • On-Line Quit Plan: Supportive texts, smartphone app and calendar,
  • Washington University Center for Smoking Cessation, 314-747-QUIT or email
  • American Cancer Society Quit For Life Program, 1-866-QUIT-4-LIFE

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Nurse Practitioner Cancer Care Clinic

Additional Information About the Role

  • Sign On Bonus Eligible
  • 12 Hour Shifts/36 Hours per week
  • Benefits Eligible

The Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine is an international leader in cancer treatment, research, prevention, education and community outreach. It is the only cancer center in Missouri and within a 240-mile radius of St. Louis to hold the prestigious Comprehensive Cancer Center designation from the National Cancer Institute and membership in the National Comprehensive Cancer Network. Parent institutions Barnes-Jewish Hospital and Washington University School of Medicine also are nationally recognized, with U.S. News & World Report consistently ranking the hospital and medical school among the nation’s elite. Employees in Oncology Services work side by side with Washington University medical oncologists providing treatment and coordination care for patients with a variety of cancers. Employees provide immediate access for patients experiencing physical and/or emotional distress due to the cancer diagnosis and assistance navigating the complex treatment plans.

OverviewPreferred Qualifications

Role Purpose


Slu Celebrates Expanded Partnership With Siteman Cancer Center

Amy Cyr, MD

Saint Louis University celebrated its expanding partnership with the Alvin J. Siteman Cancer Center with an event at the Doisy Research Center Tuesday, Feb. 14.

Dale Dorsett, Ph.D., of the department of biochemistry and molecular microbiology, presented on his work that received a Siteman Investment Program grant in 2015. Faculty and leadership from Saint Louis University, Washington University and the Siteman Cancer Center attended the event.

The event highlighted recently funded projects as well as the new opportunities available to SLU researchers interested in working with the Center. SLU recently entered into a new Memorandum of Understanding with Siteman to foster this continuing relationship.

As part of SLUs ongoing relationship with Siteman, faculty investigators have the option to compete for funding for pioneering cancer research under the centers Siteman Investment Program . Awards made under this program are for seed funds to support pilot projects that produce data that can be leveraged in larger grants and research projects.

New solicitations for the program are announced twice annually in January and July.

Faculty interested in competing for these awards must be members of the Siteman Cancer Center.

Investigators interested in becoming members of the Siteman Cancer Center or in competing for SIP funding should contact Courtney Schlueter at .

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Patient Care And Services

More than 350 Washington University research scientists and physicians provide inpatient and outpatient care at Siteman. The center also offers patient and family support services, including discussion and education groups.

In 2018, Siteman announced it would build a second proton therapy unit at its S. Lee Kling Proton Therapy Center. The first opened in late 2013.

Alvin J Siteman Cancer Center

Timothy J. Eberlein, M.D., Director

St. Louis, Missouri

In 2001, 2 years after the Alvin J. Siteman Cancer Center was established, it was named an NCI-Designated Cancer Center and was further designated a Comprehensive Cancer Center in 2005.

Siteman Cancer Center is an international leader in moving laboratory research into the clinic, including new methods and interventions to better diagnose, treat, and prevent cancer.

The center includes the cancer research, prevention, and treatment programs of Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis. Siteman treats nearly 10,000 newly diagnosed cancer patients each year, making it one of the largest cancer centers in the United States.

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Forest Park Laclede Garage

An above-ground parking structure serving our north campus, the Forest Park Laclede garage is located closest to the new Center for Outpatient Health. The entrance is located on Laclede Ave., one block northwest of Forest Park Ave. and Euclid Ave. Handicap parking is available on every level near the elevators. Clearance is 82 and it is connected to the hospital by an enclosed pedestrian walkway. Upon entering our garages, please push the button and take a ticket. A ticket is necessary to exit the garage. Depending on your appointment type, discount vouchers may be available.

An Hour To Make Pitch


Siteman learned in 2007 that federal money is not enough when it comes to high-risk research.

Leukemia researcher Dr. Timothy Ley and the co-directors of Washington Universitys genome center, Richard Wilson and Elaine Mardis, needed $1 million. Newly armed with the latest genetic sequencing machines, they wanted to sequence the first cancer genome.

Scientists had been studying a small number of genes linked to cancer, but it was a new idea to look for answers to the disease in the entire 3 billion pairs of chemical bases that make up the entire genome of a tumor.

It was risky. They were unsure what they would learn. Comparing the genome of a persons cancerous cells to that of normal cells might be too complicated. It might not reveal anything. Their application for federal funding was denied.

Still, the scientists were convinced it had to be done.

Siteman learned of their desperation, and he invited them to his Site Oil office. They had one hour to give him their best pitch.

Not sure what to expect, they were met by a man who was intensely curious about the science, engaging and intuitive.

He asked a million questions, not about the risks, but about what it all meant, what it could all lead to, what we could learn, Ley said. Hes an extremely smart man.

Siteman seemed to be testing whether they believed they could do it, they said.

You can trace it all back to Als gift, Wilson said.

He did the same with Schreiber before agreeing to fund the immunology center.

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Mesothelioma Clinical Trials At Siteman Cancer Center

  • A phase I/II clinical trial comparing the effectiveness of pembrolizumab with and without anetumab ravtansine in mesothelioma patients whose tumors test positive for mesothelin.
  • A phase II clinical trial studying the effectiveness of the combination of nivolumab and ipilimumab for patients with rare tumors, including mesothelioma.
  • A phase I/II clinical trial to determine the effectiveness of using INCAGN01876 in combination with nivolumab in patients with advanced metastatic malignancies, including mesothelioma.

Disclaimer: Watch Our Free Mesothelioma Webinars

  • 1 Barnes Jewish Hospital South St Louis, MO 63110
  • About 8,000 new cancer patients per year
  • Number of Physicians:

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