What Are The Symptoms Of Myeloma
Sometimes myeloma does not cause any symptoms. It may be found when a blood or urine test is done for another condition and a higher than normal level of protein is found. When more advanced, symptoms of myeloma may include bone pain, especially in the back or ribs bones that break easily fever for no known reason frequent infections bruising or bleeding easily trouble breathing weakness of the arms or legs and feeling very tired.
These symptoms can also come from other conditions. If you have any of them, talk to your doctor.
Low Level Of Platelets
The platelet level may also drop. If it does, you may get nose bleeds, or notice a red rash on your skin like tiny bruises. You may then need to have a platelet transfusion. After high dose chemotherapy, it can take longer for the platelet count to get back to normal than any other blood cell count.
Large Granular Lymphocytic Leukaemia
Large granular lymphocytic leukaemia is a type of blood cancer that affects white blood cells called lymphocytes.
We are currently working on some new information about LGLL. If you are affected by LGLL, or you are a healthcare professional, please get in touch with Abi on if you’d like to help shape the new information.
In the meantime, all our general information will be helpful if you have large granular lymphocytic leukaemia. We have information about what happens after diagnosis, covid and blood cancer, side effects, living well with blood cancer, watch and wait, and support for family and friends.
Our Support Service is also here for you – we can help you find out more information about large granular lymphocytic leukaemia. You can also find other people living with large granular lymphocytic leukaemia in our online community forum.
Recommended Reading: Can You Drive After Radiation Treatment
Efectos Secundarios De La Quimioterapia
La quimioterapia trata muchos tipos de cáncer de forma eficaz. Pero, al igual que otros tratamientos contra el cáncer, a menudo causa efectos secundarios. Es importante estar al tanto de los posibles efectos secundarios de la quimioterapia para que sepa a qué debe estar atento y para que pueda hablar con su equipo de atención médica sobre cómo prevenirlos y aliviarlos.
Los efectos secundarios de la quimioterapia son diferentes para cada persona. Dependen del tipo de cáncer, la ubicación, los fármacos y la dosis, y su estado de salud general.
What Causes Multiple Myeloma
While cancer research has not determined the exact cause of multiple myeloma, several factors may increase the risk of plasma cell neoplasm diseases.
The risk factors for multiple myeloma include:
- Family history, with a sibling or parent who has had the disease increasing its likelihood as much as four times when compared to people without a family history of the disease
- Personal history of monoclonal gammopathy of undetermined significance , an abnormal line of antibody-producing plasma cells that begin to produce monoclonal antibody proteins
- Radiation exposure
Also Check: Cancer Stage 4 Life Expectancy
Types Of Blood Cancer
The three main types of blood and bone marrow cancer are leukemia, lymphoma and myeloma:
- Leukemia is a blood cancer that originates in the blood and bone marrow. It occurs when the body creates too many abnormal white blood cells and interferes with the bone marrows ability to make red blood cells and platelets.
- Non-Hodgkin lymphoma is a blood cancer that develops in the lymphatic system from cells called lymphocytes, a type of white blood cell that helps the body fight infections.
- Hodgkin lymphoma is a blood cancer that develops in the lymphatic system from cells called lymphocytes. Hodgkin lymphoma is characterized by the presence of an abnormal lymphocyte called the Reed-Sternberg cell.
- Multiple myeloma is a blood cancer that begins in the bloods plasma cells, a type of white blood cell made in the bone marrow. Also, learn about the stages of multiple myeloma.
There are also less common forms of blood and bone marrow cancers, or associated disorders, including:
What Can You Do About Red Blood Cell Count After Chemo And Radiation
Doctors usually offer erythropoietic drugs to stimulate red blood cell production, but there are also things you can do on your own to increase your red blood cell count and your quality of life while going through chemotherapy.
Don’t suffer silently.
Erythropoietic drugs don’t always work very well. It doesn’t do a lot of good to be taking a hormone to increase red blood cell production if your body can’t support the higher hemoglobin levels those red blood cells need. If you don’t feel better as expected, you need blood tests sooner rather than later. Don’t keep on tolerating the symptoms your lowered red blood cell count is inducing, and ask your doctor to test you immediately.
Don’t take iron supplements or eat iron-rich foods unless you know from a blood test that your iron levels are low.
Anemia symptoms are not necessarily iron deficiency signs. It’s possible to have both cancer and hemochromatosis, a condition of high iron levels that causes, among other things, cancer, so you should not try to get extra iron unless you know from a blood test that you are deficient in iron .
Do get more iron if your blood tests show you need it.
Also Check: Pancreatic Cancer Blocking Bile Duct
How Do Blood Cancers Develop
Blood cancers develop when blood cells arent made properly.
In most blood cancers, the normal cell production is interrupted by uncontrolled growth of an abnormal type of blood cell. This can reduce the bone marrows ability to produce normal levels of other blood cells, which affects the way that the rest of the body works. Meanwhile, the abnormal cells spill out into the bloodstream.
As the abnormal blood cells build up in the blood, they can spread to the lymph glands , spleen, liver, lungs and kidneys. Without treatment, many of the bodys key functions will be increasingly affected.
How Blood Cells Normally Develop
All your blood cells start off as special cells called blood stem cells, which are made in the bone marrow .
Blood stem cells can divide and multiply in the bone marrow to produce many other blood cells. The diagram below shows how blood stem cells can grow into any of the blood cells that are needed, including white blood cells, red blood cells and platelets.
Your bone marrow makes a huge number of blood cells every second. If everythings working normally, your body makes the right number of each type of cell to keep you healthy.
If something goes wrong with the process below, blood cancer can occur, and you may get blood cells not developing properly, or multiplying too quickly.
Read Also: Act Chemo For Breast Cancer
What Are The Causes Of Anemia
Red blood cells are made in the bone marrow. Bone marrow is the soft, spongy tissue found inside your larger bones. A hormone from the kidneys, called erythropoietin, tells your body when to make more red blood cells. Damage to either the bone marrow or the kidneys can cause anemia. Anemia can be caused by cancer, cancer side effects, or cancer treatment. It can also be caused by factors unrelated to cancer.
Common causes of anemia in people with cancer include:
Chemotherapy. Chemotherapy can damages bone marrow. This damage usually does not last and anemia often improves a few months after chemotherapy ends. Also, chemotherapy with platinum-based drugs may harm the kidneys. These drugs include cisplatin and carboplatin .
Radiation therapy. Radiation therapy to large areas of the body can damage bone marrow. So can radiation therapy to bones in the pelvis, legs, chest, or abdomen.
Certain types of cancer. Leukemia, lymphoma, and multiple myeloma damage bone marrow. Also, cancer that spreads to the bone or bone marrow may crowd out healthy red blood cells.
Nausea, vomiting, and loss of appetite. Nausea and vomiting and loss of appetite may cause you to lose nutrients. Your body needs nutrients to make red blood cells. These includes iron, vitamin B12, and folic acid.
Too much blood loss. You can lose red blood cells faster than your body can make them. This may happen after surgery or if a tumor causes bleeding inside your body.
Low Level Of White Blood Cells
The level of white cell counts goes down first because many white cells naturally die off within a few days. Usually, these get replaced by new white blood cells , but cancer drugs may kill some of the developing cells.
It usually takes a week or 2 for the bone marrow to make more cells and release them back into the blood.
A drop in white blood cells can lead to an increased risk of infection.
Also Check: Last Chemo Treatment Gift Ideas
Consequences Of Cancer Treatment
If you have severe anemia, you may have to delay your cancer treatment or reduce your dose until your anemia is better managed. Anemia can cause weakness and also make some cancer treatments less effective.
Your doctor will evaluate your best course of treatment to minimize possible complications caused by cancer treatment while you have anemia.
What Is High Red Blood Cell Count
A high red blood cell count means the number of red blood cells in your bloodstream is higher than normal. Red blood cells are one of the major components of your blood, along with white blood cells and platelets. Red blood cells help carry oxygen throughout your body. But, when your red blood cell count is high, it could mean you have an underlying health condition.
Also Check: Is Cancer Detected In Blood Tests
What Is Polycythaemia Vera
Polycythaemia vera is pronounced pol-ee-sigh-thee-me-a vee-rah. Poly means many and cythaemia relates to blood cells. It is also sometimes called erythrocytosis, which means too many red blood cells.
PV is a type of rare blood disorder called a myeloproliferative neoplasm. These are conditions that cause an increase in the number of blood cells.
The World Health Organisation classes all myeloproliferative neoplasms as blood cancers. This is because the bone marrow is producing blood cells in an uncontrolled way. But many people with myeloproliferative neoplasms feel well and only need gentle treatment. The disorders often develop slowly and progress slowly. Or they can remain stable for a while.
Polycythaemia vera usually develops very slowly. It can affect people of any age. But it usually affects middle aged and older people. The average age at diagnosis is 60 years, although it can affect children and young adults.
What Is Considered A High Red Blood Cell Count
Healthcare providers measure your red blood cell count to diagnose medical conditions and learn more about your health. Whats considered normal may vary depending on where youre tested. But in general, normal red blood cell counts are:
- For people assigned male at birth, 4.7 million to 6.1 million red blood cells per microliter of blood.
- For people assigned female at birth, 4.2 million to 5.4 million red blood cells per microliter of blood.
- For children, 4.0 million to 5.5 million red blood cells per microliter of blood.
Providers typically find a high red blood cell count during testing for another health issue. You may need more tests to determine whats causing the higher levels. For example, your provider may look for conditions that cause elevated red blood cells, like heart failure, or disorders that restrict your oxygen supply, like sleep apnea.
Don’t Miss: Side Effects Of 5-day Radiation
Other Symptoms Of Blood Cancer
Many of the general symptoms of blood cancers can also be caused by other conditions, and it is important to be evaluated by a healthcare professional to determine the cause of these symptoms. In addition, not every person with blood cancer has the same symptoms. General symptoms that may be caused by certain blood cancers include:
Cancer The Blood And Circulation
This page tells you about the blood and circulation and how cancer may affect them.
There is information about
The blood flows throughout the body. It:
- carries food and oxygen to all the cells of the body
- carries away waste products that the body needs to get rid of
Without a blood supply, cells and body tissues die.
Blood Transfusions To Treat Anemia
A blood cell transfusion is a safe and a common way to treat anemia in people with cancer. It can help the patient feel better and helps oxygen get to vital organs. While blood transfusions can help symptoms very quickly, sometimes the relief is temporary depending on the cause of anemia.
Whether a blood transfusion might be needed depends on how severe your symptoms are and your hemoglobin level. A transfusion might be done if your hemoglobin level reaches a certain number or if your symptoms get too bothersome
A blood transfusion requires careful matching of donated blood to the recipients blood. Blood products are tested to be sure they are safe and the same kind of blood type as the recipient. But, receiving a blood transfusion also has some risks
How Many Kinds Of Blood Cancer Exist
There are three primary types of blood cancer:
- Leukemia is cancer of white blood cells or cells that become white blood cells. Leukemia prevents white blood cells from fighting infections in your body. Leukemia can be either acute or chronic , and affect the lymphocytes or other immune cells . Its the most common blood cancer for children under the age of 15.
- Lymphoma is cancer of the lymphatic system , particularly lymph nodes . It affects a type of white blood cell called lymphocytes. The type doctors know the most about is called Hodgkins lymphoma . Its the most common form of blood cancer in adults, accounting for over half of all diagnosed blood cancer cases.
- Myeloma is cancer of the plasma cells, which are lymphocytes that make antibodies to protect against infections. Myeloma affects your bodys immune system, leaving it susceptible to infection.
Don’t Miss: Best Moisturizer For Chemo Scalp
Cancers Stage Affects Survival And Prognosis
The cancers stage plays a big role in your prognosis, or your chance of recovery. According to the National Cancer Institute SEER Program, the average five-year relative survival rate for multiple myeloma between 2010 and 2016 was about 54 percentmeaning about 54 percent of the people diagnosed with multiple myeloma at any stage are alive five years after their diagnosis.
That survival rate changes a bit based on how far the cancer has spread. This is classified in two ways for multiple myeloma:
- Localizedonly one tumor is growing inside or outside the bone, what we defined above as a plasmacytoma. The five-year survival rate for localized multiple myeloma is about 75 percent.
- Distantmultiple tumors are found inside or outside the bones, a classic multiple myeloma. The five-year survival rate for distant multiple myeloma is lowerabout 53 percent.
Unfortunately, 95 percent of multiple myeloma cases are diagnosed at the distant stage, after it has metastasized.
Theres at least some good news on the horizonthe five-year survival rate has been improving, from around 35 percent in 2000 to 56.5 percent in 2012. Hopefully, these survival rates continue to improve with new therapies and treatment approaches. Your care team will continue to monitor you after treatment so they can ensure that your multiple myeloma hasn’t relapsed.
Expert cancer care
What Are Survival Rates For Blood Cancer
Survival rates are estimates based on averages. Your healthcare provider may share five-year survival rates as a way of explaining how your blood cancer may affect your health five years after diagnosis. Survival rates are different for each of the three blood cancer types, but many people who have blood cancer can expect to survive as long as most other people.
Read Also: Low Back Pain Cancer Symptoms
The Importance Of Cancer Screenings
Everyone should get age-appropriate cancer screenings, which can vary depending on your risk factors. Screenings are exams done on people with no symptoms. These tests can catch cancer in its early stages before it becomes severe and causes more widespread health issues.
Cancer treatments vary depending on the type of cancer.
Some common cancer treatments include:
- Chemotherapy. This treatment is the administration of anti-cancer drugs delivered through a vein to kill cancer cells.
- Radiation therapy. This therapy involves using high-powered energy beams like X-rays to kill cancer cells. Radiation therapy is often used before surgery to shrink tumors.
- Surgery. This procedure involves removing entire cancerous tumors so that they stop growing and affecting the body. Depending on where the tumor is located, this may or may not be possible.
What Is Blood Cancer
Blood cancer affects how your body produces blood cells and how well those cells work. Most blood cancers start in your bone marrow, the soft, sponge-like material in the center of your bones. Your bone marrow makes stem cells that mature and become red blood cells, white blood cells and platelets.
Normal blood cells fight infection, carry oxygen throughout your body and control bleeding. Blood cancer happens when something disrupts how your body makes blood cells. If you have blood cancer, abnormal blood cells overwhelm normal blood cells, creating a ripple effect of medical conditions. More people are living longer with blood cancer, as healthcare providers find new ways to treat it.
Also Check: Chemo For Prostate Cancer Survival Rate
What Is In Blood
Although blood looks like a red liquid, if left in a test tube it separates out into:
- a pale liquid called plasma
- a solid layer of blood cells
The blood is about 55% plasma and 45% cells. Plasma is mostly water with some proteins and other chemicals dissolved in it. There are 3 main types of cells in the blood. These are:
- white blood cells
- red blood cells
A full blood count measures the number of red cells, white cells and platelets in your blood. There are several different types of white blood cells including neutrophils and lymphocytes.
There isnt an exact value of normal for blood counts. The range of figures quoted as normal varies slightly between laboratories and also differs between men and women.