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What Is The Difference Between Radiation And Cyberknife

Why Use Cyberknife For Prostate Cancer

Summit Cancer Centers – CyberKnife vs. Gamma Knife

Cyberknife is a good option for prostate cancer because:

  • Treatment is convenient and complete in fewer fractions 5 compared to 44 fractions in traditional radiation.
  • It spares more normal tissue.
  • It is more accurate than traditional radiation.
  • There are fewer side effects.
  • Treatment is performed as an outpatient procedure.

In addition, prostate cancer is a slower-growing tumor. Because prostate cancer cells are growing slowly, they may be more sensitive to higher doses of radiation per fraction than other cancers. This means that delivering radiation in larger doses in fewer treatment sessions may improve outcomes.

Role Of Cyberknife In Liver

Stereotactic body radiotherapy has been used widely for treatment of limited metastatic diseases and hepatocellular carcinoma, which otherwise do not qualify for alternative modalities. However, the toxicity of radiotherapy at this site is significant. A number of Phase I and II studies have evaluated the role of stereotactic body radiotherapy in liver metastasis. Patients receiving doses in the range of 2025 Gy per fraction, for 3 fractions did not evidence any considerable toxicity. However, dose escalation to 30 Gy/fraction was associated with significant gastric and duodenal ulceration 3 months after SBRT. At the Princess Margaret Hospital, 41 patients with primary hepatocellular carcinoma or intraphepatic biliary cancer were treated in a Phase I dose escalation study in 6 fractions based on the effective liver volume to be irradiated. Acute elevation of enzymes occurred in 24% of patients and acute biliary obstruction was observed in 5% of patients and should be anticipated with stereotactic body radiotherapy at this site. There was one death case following gastrointestinal bleeding subsequent to duodenal ulceration which may be considered as a dose limiting toxicity.

Comparing Cyberknife To Gamma Knife

Both CyberKnife and Gamma Knife are dedicated stereotactic radiosurgery treatment technologies, but Gamma Knife is limited to only treating cancer above the ear and in the cervical spine. However, CyberKnife is the only dedicated SRS and stereotactic body radiotherapy system capable of treating cancer throughout the entire body.

Both CyberKnife and Gamma Knife are primary treatments for cancerous and non-cancerous tumors. They are also effective treatments for vascular lesions and functional disorders, such as Trigeminal Neuralgia and AVM. The commonality between the two treatments lies in the fact that both aim to eliminate tumors and to achieve an outcome similar to surgery. However, while both are highly targeted therapies, there are crucial differences between CyberKnife and Gamma Knife.

  • The principle difference between Gamma Knife and CyberKnife is that Gamma Knife requires a large metal frame be mounted onto the patients head with screws before and during treatment. CyberKnife is a non-invasive and pain-free treatment that allows patients to lie comfortably on a treatment couch while the system moves quickly around them.
  • CyberKnife patients require no general or local anesthesia during the procedure, unlike Gamma Knifes.
  • CyberKnife is a dedicated robotic system that can approach a tumor in the brain, head, neck, and spine from over 1,300 positions with pinpoint sub-millimeter accuracy. Gamma Knife is a gantry-designed system that is limited to 190 positions.
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    How Do You Prepare For Cyberknife

    Youll need to go through a few steps before treatment can begin.

    With ultrasound as a guide, a urologist will use long needles to place gold markers in your prostate. This will be similar to when you had your biopsy. CyberKnife will use the markers to track the tumor during treatment.

    Then youll need some imaging tests to assess the location, size, and shape of the tumor. This data is sent to the CyberKnife software, so the proper dose, exact location, and number of treatments can be determined.

    Your doctor will fill you in on details before you begin so you can plan accordingly.

    Youll likely need one to five treatments on consecutive days. This can all be accomplished on an outpatient basis.

    Theres no need for anesthesia or other medications, so you can eat and take medications as usual. Avoid lotions and powders on the area to be treated, and wear comfortable clothing. No further preparation is needed.

    What Is Gamma Knife

    Truebeam Stx Vs Cyberknife

    Though the name may sound like a surgical procedure, Gamma Knife is actually an advanced form of radiation therapy that uses multiple focused beams of high dose radiation to target a highly specific area.

    Because it is so focused, Gamma Knife does not affect as much of the surrounding tissue as traditional radiation therapy, such as whole-brain radiation, resulting in fewer side effects. Additionally, because it is completely non-invasive, it does not carry any of the risks associated with traditional surgery, has less post-procedural pain and has a minimal recovery period.

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    Principle In Gamma Knife Vs Cyberknife

    Gamma Knife is a gantry-designed system consists of a heavy collimator without any moving parts and its underlying principle is fairly simple it employs cobalt radiation sources in a fixed hemispherical array, such that all photon beams focus on a single point and the intracranial target coincides with the isocenter of radiation.

    Indications For Cyberknife Treatment And Current Clinical Scenario

    As of now the majority of Cyberknife treatment has been delivered to adult patients. Only 2 studies have reported its use in children between 5 months and 16 years.15 The majority of studies are also concentrated on palliative settings, although currently increasing interest is being focused on curative intent for early small volume disease, especially in benign conditions, AV malformations, trigeminal neuralgia, acoustic neuroma, meningiomas and pituitary adenomas.

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    What We Offer You For Cyberknife

    • Internationally recognized expertise and experience through developing CyberKnife treatment standards.
    • Advanced imaging technology managed by specialists in neuroradiology, cardiovascular radiology, and more.
    • Team-based treatment planning that draws on the collective expertise from radiation oncology, surgical specialties, medical oncology, interventional radiology, radiology, pathology, and supportive therapies to collaborate on your needs.
    • Comprehensive support services like occupational or physical rehabilitation, nutritional and emotional support to help you with your specific symptoms and the challenges of this experience.
    • Leading research to develop more ways to use CyberKnife, including new guidelines for radioprotectants, which protect healthy tissue from treatment and reduce radiation side effects.
    • Assistance from our International Medical Services team to plan your international travel and accommodations.


    The Stanford Medicine Online Second Opinion program offers you easy access to our world-class doctors. Its all done remotely and you dont have to visit our hospital or one of our clinics for this service. You dont even need to leave home!

    Visit our online second opinion page to learn more.

    Technical Aspects Of Sbrt

    IMRT vs SBRT vs Protons vs Brachytherapy | Ask a Prostate Expert, Mark Scholz, MD

    Stereotactic body radiotherapy uses a 3-dimensional co-ordinate system utilizing internal fiducials or image guidance for tumour tracking and treatment delivery. Cyberknife has the advantage over other SBRT systems in that it is capable of tracking the co-ordinates in real time while the head of the accelerator re-aligns itself to accommodate fluctuations in target position. The delivery of SBRT generally utilizes multiple noncoplanar arcing fields directed at the radiation target. As a result, the dose gradient is much deeper than conventional radiation and irregularly shaped. The dose with SBRT is generally prescribed to the isodose line encompassing the target which allows for an inhomogenous dose delivery in which the core of the target receives a much higher dose. This may be especially advantageous when anticipating a hypoxic core that may harbour resistant clonogens. Stereotactic body radiation fractionation uses doses that may range from 5 to 30 Gy/fraction and often takes into consideration the BED offered by dose escalation.

    Stereotactic body radiotherapy is the best tool for sparing parallel normal tissue, abutting planned large volumes. Even several tissues like lung, liver and kidney may benefit when functional subunits are maximally preserved by the deep dose gradients.

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    Prostate Cancer Treatment Near Me

    Proton therapy and CyberKnife are both options for prostate cancer treatment. But the experts at CyberKnife Miami recommend getting a second opinion and a consultation to see which treatment is right for you from a lifestyle and cost perspective.

    We are happy to be your second opinion and answer any questions you may have about all prostate cancer treatment options, and which one is right for your particular case.

    If you are diagnosed with prostate cancer, call CyberKnife Miami for a consultation. Our goal is to get you back to your life cancer free with minimal to no downtime.

    If you would like to find out more about prostate cancer treatment with CyberKnife, call us at 305-279-2900 or go to our prostate cancer website now for more information.

    With The Beam of Life, CyberKnife Miami is giving thousands of people new hope in treating various cancers where there was none. Visit the CyberKnife Center of Miami located in Miami, Florida.

    Gamma Knife Vs Cyber Knife

    Competition to treat benign and malignant brain lesions, vascular malformations, and functional conditions with stereotactic radiosurgery has increased dramatically in recent years. All-in-one systems like the Accurays CyberKnife are aggressively positioning themselves as being comparable to the Leksell Gamma Knife® in effectiveness and efficiency.

    As one of the earliest and most experienced Gamma Knife centers in the world, we at the University of Virginia wish to address the competing LINAC based technologies such as Cyberknife.

    Gamma Knife surgery is the gold standard for the treatment of intracranial pathology. Its clinical efficacy has been documented across nearly four decades, with more than 400,000 cases treated worldwide providing the data for 2,000+ publications in peer-reviewed medical literature. It is used as the performance standard against which other technologies are measured.

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    Who Is A Candidate For Cyberknife

    CyberKnife can be used as a first-line treatment for early-stage prostate cancer. It can be combined with hormone therapy for cancer that has spread into nearby tissues. It can also be used to slow progression in advanced cancer or cancer that has recurred after previous treatment.

    Prostate cancer treatment is not the same for everyone. Surgery, radiation therapy, chemotherapy, and hormone therapy are designed to do different things.

    There are a few benefits of CyberKnife when compared to other treatments:

    • Theres no incision or pain, as you might have from surgery.
    • Theres no need for anesthesia or a hospital stay.
    • As soon as its over, you can get up and return to your normal activities.
    • Its a lot less time-consuming than conventional radiation or chemotherapy.
    • Theres no extended recovery period.

    Another type of radiation used for prostate surgery is brachytherapy. It involves implanting radioactive pellets in your prostate. The pellets release radiation over a period of days or weeks. Its a good option for early-stage or low-grade prostate cancer. CyberKnife may be a better choice if you cant have anesthesia or if your anatomy makes brachytherapy difficult.

    If you have treatment with CyberKnife, you may need other therapies as well. Your doctor will make a recommendation based on variables such as the stage and grade of the cancer, as well as your age and any other health conditions you may have.

    Cyberknife Vs Other Types Of Radiation For Prostate Cancer

    Truebeam Stx Vs Cyberknife

    by Prostate Cancer Center | Jan 18, 2022 | CyberKnife Center of Miami, CyberKnife For Prostate Cancer, CyberKnife Treats Prostate Cancer

    Radiation is a powerful tool in the fight against prostate cancer with a proven track record of safety as well as an excellent cure rate.

    However, when doctors talk about radiation for prostate cancer, you should know there are different radiation treatments available. They fall into two main categories, according to the American Cancer Society: internal radiation and external beam radiation.

    Internal Radiation or Brachytherapy: With internal radiation doctors place small radioactive pellets or seeds into the prostate. This treatment is used for men with early-stage, slow-growing cancers. It can also be combined with external radiation for men with a greater risk of the cancer spreading.

    External Beam Radiation Therapy : This radiation is focused on the prostate gland from outside the body. EBRT is often used for earlier staged cancers or to help relieve symptoms like bone pain if the cancer has spread. There are several types of external radiation used for prostate cancer.

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    What Is Proton Therapy

    Both CyberKnife and Proton are forms of radiation , however, CyberKnife has many advantages over proton beam radiation as a prostate cancer treatment. CyberKnife is the most advanced treatment available, using image-guided robotics to destroy prostate cancer while preserving the surrounding tissue.

    Proton Therapy is a type of particle therapy in which high-energy proton beams are delivered to tumors by a cyclotron. With Proton Therapy, doctors determine the precise point in a patients body where the proton releases the majority of its energy, maximizing exposure to cancer cells while minimizing exposure to normal tissue. Proton Therapy is usually delivered in 20-25 treatments with typical out-patient sessions lasting less than 5 minutes. Side effects such as fatigue are usually minor and temporary.

    Proton beam therapy utilizes lower doses of radiation, so more treatments are required. These treatments use conventional fractionation with small doses given daily over a four to six week period.

    The chart shows the differences between CyberKnife and Proton Therapy treatments. As you can see, CyberKnife Therapy is completed in fewer sessions with better accuracy and the CyberKnife is the only technology where there is continuous correction during treatment while the prostate moves and the patient breathes normally.

    Treatment Of Gamma Knife Vs Cyberknife

    Both Gamma Knife and CyberKnife are the dominant methods of stereotactic radiosurgery used to treat malignant brain tumors and other functional abnormalities in the brain. However, Gamma Knife is a frame-based radiosurgery technique that requires the application of an invasive frame to the patients head to achieve the desired accuracy. On the contrary,

    CyberKnife is an innovative frameless radiosurgical system that provides precise target lineation without the need for a rigid stereotactic frame for immobilization. Additionally, in contrast to the frame-based Gamma Knife method, the high-dose treatments with CyberKnife could be divided into more fractions to control tissue dose, thereby reducing toxicity from treatment.

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    How Does Sbrt Cyberknife Compare To Traditional Radiotherapy

    Cyberknife is a form of targeted radiation therapy known as SBRT. SBRT, or stereotactic body radiation therapy, was adapted from central nervous system stereotactic radiosurgery, a treatment technique that has been used to treat tumors of the brain and central nervous system for over 30 years. The only real difference is that SBRT is used to treat tumors throughout the rest of the body instead of specifically in the brain.

    How does SBRT compare to traditional radiation therapy? SBRT delivers radiation directly to the cancerous tissue, sparing the healthy tissue around it. As a result, it can be administered in fewer sessions, with fewer side effects, and with higher success rates.

    What Happens After Treatment

    Dr. Jim Hu – Surgery Vs Cyberknife, Radiation for Prostate Cancer

    Treatment with CyberKnife generally doesnt interfere with normal activities.

    Your doctor will advise you on a follow-up schedule of visits. A few months after treatment, youll probably need to schedule new imaging tests, such as CT, MRI, or PET. The images will help your doctor evaluate your response to radiation treatment.

    If no cancer can be found, you may not need further treatment. Youll need careful monitoring for some time, though. That usually involves routine physical exams, PSA testing, and imaging tests to check for signs of recurrence.

    If theres still evidence of cancer after SBRT, your doctor will make some recommendations on the next steps.

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    Cyberknife Procedure & Treatment Planning

    Your Mercy care team will include your surgeon, radiation oncologist, medical oncologist, physicist, the CyberKnife team and other clinical professionals.

    Before your CyberKnife procedure, you’ll have a CT simulation to determine the size, shape and location of the tumor. The CT simulation is also used to create a custom immobilization mask or a body mold to help minimize movements and enhance your comfort. Additional imaging such as an MRI or PET scan may also be needed.

    Your images are digitally transferred to CyberKnifes system, where an individualized treatment plan is created.

    Wear comfortable clothing, and dont wear any jewelry. Youll be comfortably positioned on the treatment table as the CyberKnifes robotic arm slowly moves around your body in various locations to deliver radiation to the tumor.

    Your CyberKnife session will last from 30 minutes to an hour, depending on your type of cancer tumor. If your treatment is delivered in stages, youll return for additional treatments over several days, based on your doctors instructions.

    After you leave the CyberKnife suite, you can typically resume normal activities the same day or soon after. Additional imaging may be needed after your CyberKnife treatments, as directed by your Mercy doctor.

    Cyberknife Therapy For Prostate Cancer

    CyberKnife has been used worldwide to successfully treat hundreds of thousands of prostate cancer patients.

    At the CyberKnife Center of Miami, we have treated hundreds of prostate cancer patients in the South Florida area with excellent results.

    We treat patients from across the country as well as right here in Miami-Dade, Broward, Palm Beach and Monroe counties. Our staff is here to answer

    any of your questions, and we are happy to offer a second opinion.If you would like to find out more about prostate cancer treatment with CyberKnife,

    call us now at 305-279-2900 or go to our prostate cancer website now for more information.

    With The Beam of Life, CyberKnife Miami is giving thousands of people new hope in treating various cancers where there was none. Visit the CyberKnife Center of Miami located in Miami, Florida.

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    Efficacy In Pancreatic Tumours

    Radiation can play an important role in palliation of pancreatic carcinoma or even prophylactic palliation of local regression, biliary obstruction, and splanchnic nerve pain. Stereotactic body radiotherapy has the advantage of improved local control and is more patient friendly in terms of shorter treatment time, faster palliation and better normal tissue sparing. Two Phase II studies by Aarhus University18 and Stanford University19 show conflicting reports regarding toxicity. Surprisingly, the Stanford protocol with single fraction treatment has lesser toxicity than the Aarhus protocol of 45 Gy in 5 fractions. The disparity only highlights the multitude of variables that may have to be taken into account when designing a stereotactic radiotherapy treatment protocol. Carcinoma Pancreas Phase II studies suggest a dose escalation advantage with doses of 25 Gy achieving 85% local control vs. 66% for 20 Gy and 70% for 15 Gy.20

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